FEATURES OF APPLICATION OF AUTOLOGICAL MESENCHEMAL STEM CELLS IN TREATMENT OF SYMPTOMATIC EPILEPSY, CLINICAL CASE

Abstract

Pharmacological-resistant epilepsy cases require alternative therapies. A modern high-tech method of treating symptomatic epilepsy has been developed and successfully applied in Belarus. This is the transplantation of autologous mesenchymal bone marrow stem cells, which can be obtained in sufficiently large quantities and set the direction of their differentiation into neurons.

Below is a description of a clinical case of a 24 years old patient with epilepsy. The patient has secondary generalized tonic-clonic and tonic convulsive seizures due to perinatal pathology against the background of developed pharmacoresistance to antiepileptic drugs. Treatment with autologous mesenchymal bone marrow stem cells significantly improved the patient's condition: generalized tonic-clonic and tonic seizures stopped. After the repeated administration of autologous mesenchymal bone marrow stem cells stable clinical remission has come. It can be assumed that treatment with autologous mesenchymal stem cells helps to overcome resistance to antiepileptic drug therapy.