Detection of herpes viruses in patients with myalgic encephalomyelitis /chronic fatigue syndrome in Belarus
Abstract
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a multifactorial chronic disease. The etiology and pathogenesis of ME/CFS are unknown . There are many theories for the occurrence of this disease. but the most convincing is the infectious or viral theory of the emergence of CFS.
The aim of this study is to detect of herpes viruses 6, 7 types and Epstein-Barr to examine the prevalence HHV-6, HHV-7 and EBV infections in Belarus CFS patients .
We examined 30 patients with CFS in whom fatigue during more than 2 years (7), more than 1 year (11) and more than 6 months (12). The diagnosis was made on clinical grounds using the Fukuda criteria.
The presence of markers the active forms infection HHV-6 and HHV-7 in CFS patients with a long period of fatigue were detected in 16.6% and 26.6% respectively. IgM antibodies to HHV-6 and EBV. positive, in 16.6% and 6.7% respectively in patients with long-term illness. Detection of IgG antibodies indicates a quiet carrier state, latent phase.
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